Boes Lab

21 Apr 2024

photo lab diner 2024

Terrific food and people at our yearly lab dinner of April 19 2024

04 Oct 2023

HORIZON-HLTH grant awarded!

Exciting news! I am thrilled to announce that our consortium has been awarded a 5-year Horizon-HLTH 2023 grant from the European Commission (€ 7 million) for our project, Causative Link between respirAtory syncytial viRus and chronic lung diseases: Identifying Targets for therapY: CLARITY

15 Apr 2023

Boes lab outing 2023

April 14 2023

19 Mar 2023

Team UMC-Utrecht, at the Hollandse 100 of 2023! with Anniek Stuut, Leon Raijmakers, Thomas Kimman, Patrick Greve and Marianne Boes

We had a team together from UMC-Utrecht to participate in this years' Hollandse 100, a fundraising event organized by the Lymph&Co foundation!

22 Jan 2023

Chinese New Year's Dinner, in Amsterdam

First social gathering of 2023

10 Dec 2022

Boes lab Holiday Season Outing 2022

With St Nicholas poems included!

10 Dec 2022

PhD defense of the wonderful Francesca Ververs! Dec 6 2022

PhD Defense: Emerging insights into early atherosclerosis in adolescents with chronic disease

Francesca Alexandra Ververs

Tuesday 6 December 2022 from 10:15 to 11:15

Atherosclerosis is a life-long disease process. It remains subclinical for years and presents only after the first decades of life as peripheral artery disease, ischemic heart disease (heart attack), or stroke, together known as cardiovascular disease (CVD). Chronic disease may accelerate atherogenesis due to the presence of inflammatory, metabolic, or hemodynamic risk factors.

14 Oct 2022

Marianne nominated for supervisor of the year 2022!

secretly, the lab nominated Marianne for 'PhD supervisor of the year 2022' at Utrecht University

10 Jul 2022

Boes Lab BBQ, with the Boxem lab

We had a wonderful BBQ-party (more vegan than meat) on July 8 2022. So happy with this bunch of talented people...

08 May 2022

PhD defense of the translational immunology-talent Juliette Pouw!! Sept 1 2022

PhD Defense: Unravelling the complexity of psoriatic arthritis on a journey towards precision medicine

PhD supervisor(s) dr. M.L. Boes and prof. dr. J.M. van Laar

Co-supervisor(s): dr. E.F.A. Leijten and dr. J. Spierings

06 Dec 2021

PhD thesis defense of the terrific Sarah Schep! Dec 23 2021

Inhibitors and Immune Tolerance Induction in Hemophilia A: A balancing act Remmers en Immuun Tolerantie Inductie in Hemofilie A: Een delicate balans (met een samenvatting in het Nederlands) Proefschrift ter verkrijging van de graad van doctor aan de Universiteit Utrecht op gezag van de rector magnificus, prof.dr. H.R.B.M. Kummeling, ingevolge het besluit van het college voor promoties in het openbaar te verdedigen op donderdag 23 december 2021 des middags te 2.15 uur door Sarah Judith Schep geboren op 10 april 1987 te Gorinchem. Promotoren: Prof. dr. R.E.G. Schutgens Prof. dr. J.J. Voorberg Copromotoren: Dr. M.L. Boes Dr. K. Fischer

25 Nov 2021

PhD thesis defense of the fabulous Nila Servaas! November 25 2021

Unveiling the two faces of immune dysregulation in Systemic Sclerosis A multi-omics approach Onthulling van de twee gezichten van immuunontregeling bij Systemische Sclerose Een multi-omics benadering (met een samenvatting in het Nederlands) Proefschrift ter verkrijging van de graad van doctor aan de Universiteit Utrecht op gezag van de rector magnificus, prof.dr. H.R.B.M. Kummeling, ingevolge het besluit van het college voor promoties in het openbaar te verdedigen op donderdag 25 november 2021 des middags te 4.15 uur door Nila Hendrika Servaas geboren op 30 juni 1993 te Gouda

10 Nov 2021

PhD defense of the wonderful and talented Emmerik Leijten on June 29 2021!

Psoriasis and PsA have predominantly shared genetic background and overlapping immunologic signature, confirming their denomination as falling within a spectrum of one single disease. Local tissue factors induce a primary inflammatory response, followed by a persistent inflammatory environment that hosts innate and adaptive immune cells with overlapping functional effects. The local inflammatory process of the tissue is capable of determining the phenotype, where psoriasis and/or arthritis can occur in an independent fashion both from clinical and pathophysiological point of view. In the circulating compartment we detected only subtle changes between patients with psoriasis compared to PsA. Main phenotypic manifestations should drive study participant selection for both clinical and basic research questions, without the need to dichotomize PsA versus psoriasis. Promotors: prof. dr. Timothy Radstake and dr. Marianne Boes, UMC Utrecht.

16 May 2021

new paper published on immunometabolism in chronic inflammatory disease, by Francesca Ververs et al!

Invariant Natural Killer T (iNKT) cells respond to the ligation of lipid antigen-CD1d complexes via their T-cell receptor and are implicated in various immunometabolic diseases. We considered that immunometabolic factors might affect iNKT cell function. To this end, we investigated iNKT cell phenotype and function in a cohort of adolescents with chronic disease and immunometabolic abnormalities. We analyzed peripheral blood iNKT cells of adolescents with cystic fibrosis (CF, n = 24), corrected coarctation of the aorta (CoA, n = 25), juvenile idiopathic arthritis (JIA, n = 20), obesity (OB, n = 20), and corrected atrial septal defect (ASD, n = 25) as controls.